COVID Vaccination in Pregnant and Breastfeeding Individuals


As U.S. vaccine distribution expands to include younger healthier populations, questions about vaccine safety in women of childbearing age have become more urgent. @UTSWMed’s Catherine Y. Spong, MD and @Emory Healthcare’s Denise J. Jamieson, MD, MPH, both eminent obstetrician/gynecologists, join JAMA’s Q&A series to discuss the safety of the Pfizer/BioNTech and Moderna vaccination in pregnant and nursing moms, and in women trying to get pregnant. Recorded February 8, 2021.

Topics discussed in this interview:
0:00 Introduction
0:55 Viewpoint co-authored by Dr Jamieson
2:16 Viewpoint co-authored by Dr Spong
3:09 Risks of COVID-19 for pregnant persons and fetuses
6:35 Zika and pregnancy, differences from COVID-19
8:14 Delivery and postpartum for COVID-19-positive pregnant persons
11:35 Testing for vertical transmission
12:32 COVID-19 vaccines and pregnancy
15:50 Advice to pregnant persons about COVID-19 vaccines
18:55 Vaccine availability across States
20:12 Differentiating between vaccines
22:08 Professional society recommendations
23:04 Legal liability, risks versus benefits
25:04 Vaccine preferences among pregnant persons
28:00 Previous infection and vaccination in pregnant persons
29:29 Vaccinated individuals helping with infant care
31:23 Breastfeeding and vaccine risks
32:37 Excluding pregnant and lactating persons from clinical trials
34:14 Ongoing trials
35:36 Can vaccinated family members transmit COVID-19
36:28 Antibodies in breastmilk
37:10 Surprises with COVID-19 and pregnancy

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